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GenScript corporation sds-page gels m00653
Sds Page Gels M00653, supplied by GenScript corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/sds-page+gels+m00653/expressplustm+page+gel+m42012/pm40338735-263-6-8
Average 90 stars, based on 1 article reviews
sds-page gels m00653 - by Bioz Stars, 2026-09
90/100 stars

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Article Title: Discovery and Characterization of RP03707: A Highly Potent and Selective KRAS G12D PROTAC.
Article Snippet: KRASG12D, the most prevalent oncogenic mutation in KRAS-associated tumors, represents a highly sought-after drug target for cancer treatment.. In this study, we explored a KRASG12D protein degradation approach using the PROTAC technology for the treatment of KRASG12D mutant tumors.. Through the rational design of the KRASG12D binder and proper selection of the linker and the E3 ligase ligand, we constructed PROTACs and identified RP03707 as a CRBN-involving, highly potent, and selective KRASG12D degrader.



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